Epidemiological and Clinical Considerations of COVID-19 in Patients with Diabetes Mellitus
Keywords:
coronavirus disease, SARS-CoV-2, COVID-19, diabetes mellitus type 2, Mellitus diabetes.Abstract
Introduction: Patients with diabetes mellitus have a predisposition to viral, bacterial and fungal infections. In the face of the COVID-19 pandemic, it has been shown how diabetes is a common comorbidity among those affected by this disease.
Objective: To describe the relationship between COVID-19 and diabetes mellitus.
Methods: A bibliographic review was carried out from February to May 2021. Open access scientific articles available in SCOPUS and PubMed databases were consulted. Original research, meta-analyses, reviews, consensus guidelines and summary documents from official organizations and scientific societies were included. Sixty publications were worked on, in total.
Conclusions: Observational studies have provided evidence in favor of the relationship between diabetes and the risk of developing severe forms of COVID-19. This susceptibility involves pathophysiological factors that include the pro-inflammatory state that is generated in diabetes, the overexpression of ACE2, and the cytokine storm. The risk is greater in elderly, male patients, with other comorbidities, socioeconomic vulnerability and poor glycemic control (HbA1c > 7%). Health professionals related to the assistance and care of patients with diabetes must stay updated and guide their patients in care measures, to reduce the risk of contagion and, in that case, the incidence of severe forms of the disease.
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